Product Usage: This product is intended solely for use as a research chemical. It is designated exclusively for in vitro research and laboratory testing. All information provided on this site is for educational purposes only. It is strictly prohibited to administer this product to humans or animals. Only licensed and qualified professionals should handle it. This product is not classified as a drug, food, or cosmetic and must not be misrepresented or used as such. This product is for research use only. Not for human consumption.
AOD9604 5mg
AOD9604 is a laboratory-created peptide that is built from the 176–191 segment of human growth hormone and includes a stabilizing disulfide bond. It was initially examined for its potential to assist with fat reduction, but research has also looked at its possible role in supporting heart function, joint and cartilage health in osteoarthritis, and broader metabolic balance. Animal studies suggest that it encourages the body to break down stored fat for energy while at the same time reducing the biological processes that lead to the accumulation of new fat tissue.
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What is AOD9604?
AOD9604 is a laboratory-designed peptide based on a specific fragment of human growth hormone, adapted to emphasize effects on fat metabolism. It was first explored as a candidate for managing excess body fat because it encourages the breakdown of stored fat without significantly influencing insulin or insulin-like growth factor activity. This selectivity suggests it may help support fat loss while having a relatively limited impact on blood sugar control, and its close structural similarity to naturally occurring growth hormone means it is less likely to provoke an unwanted immune response.
AOD9604 Structure
Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Disulfide bridge Cys7-Cys15
Molecular Formula: C78H123N23O23S2
Molecular Weight: 1815.12 g/mol
PubChem CID: 16131447
CAS Number: 386264-39-7
AOD9604 Research
1. AOD9604 and Obesity
This peptide was originally created as a modified growth hormone fragment with the primary goal of assisting weight management. In mid-stage clinical work involving a sizeable group of adults with obesity, once-daily dosing over several weeks produced greater average weight reduction compared to placebo, and the pace of weight loss remained steady throughout the observation period. These findings suggest that the body does not quickly adapt to or resist its effects, raising the possibility that extended use under appropriate conditions could lead to more substantial fat loss.
2. Joint Pain and Function
Preclinical research in animals with experimentally induced joint degeneration has shown that injecting AOD9604 directly into affected joints can complement existing treatments. In these models, the peptide has been associated with reduced pain-related behaviors, improved mobility, and measurable changes in cartilage structure that are consistent with healthier joint tissue. Although it appears to have beneficial effects on its own, outcomes are often better when AOD9604 is combined with other joint-supporting therapies, suggesting a synergistic potential and pointing to new avenues for exploring cartilage repair strategies.
3. AOD9604 and Heart Health
While reducing excess fat and body weight is known to lower cardiovascular risk, investigations suggest that AOD9604 may have additional influences on metabolic processes that are relevant to heart health. Some findings indicate that it could improve certain metabolic markers independently of its role in fat loss, similar to how other compounds can modify metabolic risk factors without necessarily causing weight reduction. The alternative pathways through which AOD9604 promotes changes in fat tissue, beyond beta-3 adrenergic receptor activity, are of particular interest for their potential impact on broader metabolic balance.
In animal testing, AOD9604 has generally shown a favorable tolerability profile, with good absorption when given orally and effective uptake when administered by injection. Dosages used in animal experiments cannot be directly translated to appropriate amounts for human use. This compound is intended strictly for controlled laboratory and scientific research and is not approved for human consumption or therapeutic application.
Factor Peptides Storage Guidelines:
These peptides arrive in a dried, stabilized form produced by a process called lyophilization, or freeze drying. In this state, they are generally suitable for transport and short-term storage at typical room temperatures for several months.
Once the dry powder is mixed with bacteriostatic water and turned into a liquid solution, the storage requirements change. The reconstituted solution should be kept in a refrigerator to help maintain its properties, and is usually considered suitable for use for about 30 days under chilled conditions.
Lyophilization involves freezing the material and then exposing it to low pressure so that ice in the sample passes directly from solid to vapor, rather than melting. This leaves behind a light, porous, white solid that is more stable than the original liquid. In this form, the product can often be kept at room temperature until it is time to add diluent.
After delivery, it is good practice to protect the vials from heat and strong light. If the product will be used in the near future, storing the lyophilized powder or reconstituted solution in a refrigerator at temperatures below about 4°C (39°F) is typically appropriate. The dry form often remains intact at room temperature for a number of weeks, so this may also be acceptable when immediate refrigeration is not available and the intended use is relatively soon.
For storage over longer periods, such as many months or years, much colder conditions are preferred. Placing the vials in a deep freezer, around -80°C (-112°F), is commonly used to help preserve the structure and activity of peptides for extended time frames.