GHK-Cu

GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (Gly-His-Lys, or GHK), a short three-amino-acid sequence first isolated from human plasma. The free peptide has an exceptionally high affinity for copper(II) ions, and in the GHK-Cu form the tripeptide chelates a single copper atom to give the characteristic blue complex. Because of this copper-binding identity, GHK-Cu is classified among the copper-peptide research compounds and is supplied here as a reference material for laboratory investigation.

In preclinical and in-vitro research, GHK-Cu has been studied extensively as a tissue-signaling molecule. Reported experiments in dermal fibroblast cultures and rodent wound models have examined its association with collagen synthesis (types I and III), glycosaminoglycan and proteoglycan expression, fibroblast activity, and angiogenesis-related pathways such as TGF-beta signaling. Investigators have also explored GHK-Cu in models of skin remodeling, antioxidant and anti-inflammatory activity, and gene-expression modulation. These observations derive exclusively from cell-culture and animal studies; no claims of human efficacy are made or implied, and all findings should be interpreted as research observations rather than established outcomes.

Specifications: Copper(II) complex CAS 89030-95-5 (free tripeptide GHK CAS 49557-75-7) · Free tripeptide molecular formula C14H24N6O4 · Free tripeptide molecular weight 340.38 g/mol · Copper(II) complex molecular formula C14H22CuN6O4 · Copper(II) complex molecular weight approx. 401.91 g/mol · Sequence Gly-His-Lys (3 amino acids) · Purity >=98% (HPLC) · Form lyophilized powder · Available sizes 100 mg, 50 mg

Storage and handling: Store the lyophilized powder at -20C and protect from light. Reconstitute with bacteriostatic (BAC) water; keep the reconstituted solution refrigerated and use within a few weeks. Avoid repeated freeze-thaw cycles to preserve integrity.

For research use only. Not for human consumption. This product is not a drug, food, or dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease.