N-Acetyl Epitalon 5 mg

N-Acetyl Epitalon is a synthetic, N-terminally acetylated analog of Epitalon (Epithalon), a short tetrapeptide built on the amino-acid sequence Alanine-Glutamic acid-Aspartic acid-Glycine (Ala-Glu-Asp-Gly, or AEDG). The parent peptide was derived by Russian researchers at the St. Petersburg Institute of Bioregulation and Gerontology from the amino-acid analysis of epithalamin, a peptide preparation isolated from the pineal gland. In the N-acetyl form, an acetyl group is added to the N-terminus of the four-residue chain, a modification commonly used in peptide chemistry to alter charge, lipophilicity, and resistance to aminopeptidase activity relative to the unmodified peptide.

In preclinical and in-vitro research, the Epitalon (AEDG) peptide family has been investigated as a candidate telomerase activator and as a model compound for studying telomere dynamics in cultured human cells. Laboratory studies have also examined its proposed role in modulating gene expression, circadian and pineal regulatory pathways, oxidative-stress responses, and the development of spontaneous tumors in rodent models. The N-acetyl variant is studied as a structurally stabilized tool compound for such investigations into cellular senescence, geroprotection, and peptide-receptor interactions. All reported effects are observations from cell-culture and animal research and have not been established in humans.

Specifications: Molecular formula C16H24N4O10 · Molecular weight 432.38 g/mol · Sequence Ac-Ala-Glu-Asp-Gly (N-acetylated AEDG tetrapeptide) · Purity >=99% (HPLC) · Form lyophilized powder · Available sizes Default

Storage & handling: store the lyophilized powder at -20C and protect it from light. Reconstitute with bacteriostatic (BAC) water; keep the reconstituted solution refrigerated and use it within a few weeks.

For research use only. Not for human consumption. This product is not a drug, food, or dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease.